Sherpani Col and Amphulaptsa pass trek is one of the most adventurous trek in the high Himalayas which is only suitable for experienced trekkers and climbers. During this trek you will enter the highest valley in the world to begin your journey to the base of Mt. Makalu, the fifth highest mountain in the world (8481m).
| Days | Itinerary | |
| 1 | Flight Kathmanu-Tumblingtar - Kandbari | 1040m |
| 2 | Chichilla | 1700m |
| 3 | Num | 1450m |
| 4 | Seduwa | 1510m |
| 5 | Tashigaon | 2070m |
| 6 | Restday - extra day | 2070m |
| 7 | Kauma kharka | 3440m |
| 8 | Mumbuk | 3500m |
| 9 | Nehe kharka | 3450m |
| 10 | Langmale kharka (Yak Kharka) | 4300m |
| 11 | Makalu basecamp | 4700m |
| 12 | Acclimatisation day - extra day | 4700m |
| 13 | Upper Barun glaciercamp (Sandy camp) | 5250m |
| 14 | East glacier camp | 5700m |
| 15 | Acclimatisation day - extra day | 5700m |
| 16 | Over East- en Westcol - Baruntse basecamp (5300m) | 6150m |
| 17 | Seto Pokharai | |
| 18 | Amphulaptsa BC | |
| 19 | Cross Amphulaptsa & to Imja Valley | |
| 20 | Thyangboche | |
| 21 | Namche | |
| 22 | Lukla | |
| 23 | Fly back to Kathmandu |
